Women's Reproductive Sciences Research: Mysorekar Lab
England Lab, Washington University School of Medicine
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Urothelial stem cell regeneration

Urothelial stem cell regeneration

Mysorekar lab is using a multipronged approach to understand the cellular and molecular details of adult stem cell biology of the mammalian urinary bladder. The bladder is lined by a pseudo-stratified transitional urothelium continuously repopulated by a urothelial stem cell (USC).

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Autophagy and pathogenesis of UTIs

Autophagy and pathogenesis of UTIs

We also focus on a complication of UTIs, namely, their propensity to recur frequently in a subset of patient population. Clinically, these recurrent UTIs and de novo acute infections are both thought to be due to re-contamination of the urinary tract from the intestinal reservoir.

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Infection and Pre-term Birth

Host-pathogen interactions at maternal-fetal interface

Another long-term goal of the lab is to elucidate the mechanisms underlying preterm birth (PTB), a leading cause of perinatal morbidity and mortality in developing countries, to develop targeted therapeutic modalities and ultimately limit the burden of PTB.

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Indira's Lab Picture Nov 2014

About Us

Our work encompasses studies of mechanisms underlying biology and pathophysiology of the urinary bladder to studies of novel infectious etiologies for premature birth .

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